The Cost Of Growing Up

Study reveals an alarmingly high prevalence of asthma, allergic diseases and obesity in adolescent children, suggesting a link between air pollution, obesity, asthma and other allergic diseases.

Planet Outlook
September 01, 2021
The Cost Of Growing Up

Millions of school children across India will return to school today, while we have been concerned about their safety with reference to COVID-19 before letting them go back to school, another invisible killer has been impacting their health severely and slowly. Studies across the world prove that Air Pollution is stunting our children’s brains, impacting their neurodevelopment and cognitive ability and can trigger asthma, and childhood cancer.  Children who have been exposed to high levels of air pollution may be at greater risk for chronic diseases such as cardiovascular disease later in life. One reason why children are particularly vulnerable to the effects of air pollution is that they breathe more rapidly than adults and so absorb more pollutants. 

A study evaluating the lung health status of 3157 adolescent school children has revealed alarming findings showing high prevalence of symptoms related to asthma and allergy, airway obstruction/asthma, and childhood obesity.  “This study is an eye-opener. It has shown an unacceptably high prevalence of respiratory and allergic symptoms, spirometry-defined asthma, and obesity in Delhi Children. Air Pollution is the probable link with all three. It is high time that the air pollution issue in Delhi and other cities is settled in a systematic manner to save the future of our children,” said Dr. Arvind Kumar, Founder Trustee Lung Care Foundation & Chairman – Institute of Chest Surgery, Medanta, Gurugram.

Lung Care Foundation and Pulmocare Research and Education (PURE) Foundation conducted the study across 12 randomly selected schools in Delhi, Kottayam, and Mysuru. The primary aim of the study was to assess the respiratory health of adolescent school children studying in private schools in the city of Delhi and compare them with relatively cleaner cities in terms of particulate matter air pollution, viz: Kottayam and Mysuru. The study was funded by Shakti Sustainable Energy Foundation and got published in a leading a peer-reviewed medical journal, Lung India, on 31st August 2021. “This is one of the first studies in India among adolescent school children that has shown a strong association between obesity and asthma, and that air pollution may have a direct link between the two. Breathing polluted air can make children fat and this may increase their risk of developing asthma,” said Dr Sundeep Salvi, Director, Pulmocare Research and Education (PURE) Foundation, Pune.

3157 adolescent school children were examined in the study to assess their lung health. All children completed a comprehensive questionnaire, that was based on a standard, validated questionnaire developed by the International Study for Asthma and Allergic Diseases in Children (ISAAC). All children also underwent an on-site spirometry, which is the gold standard test to assess lung function, by certified technicians and nurses.

 

KEY FINDINGS OF THE STUDY

Key Finding 1: Questionnaire Related: An alarmingly high number of children reported asthma and allergy related symptoms: 

    • In Delhi: 52.8% school children reported sneezing, 44.9% reported itchy watery eyes, 38.4% reported significant cough, 33% reported itchy rash, 31.5% reported shortness of breath, 11.2% reported chest tightness, and 8.75% reported eczema.
       
    • In Kottayam & Mysuru: 39.3% school children reported sneezing, 28.8% reported itchy watery eyes, 18.9% reported significant cough, 12.1% reported itchy rash, 10.8% reported shortness of breath, 4.7% reported chest tightness, and 1.8% reported eczema. 
    • Delhi school children have significantly higher prevalence of Asthma and allergy symptoms as compared to school children in Kottayam and Mysuru.


Figure 1: Prevalence of Asthma and Allergy related symptoms in school children in Delhi, and Kottayam - Mysuru.

 

Key Finding 2: Spirometry Data: High prevalence of air flow obstruction/ asthma: 

    • 29.3% children from Delhi were found to have airflow obstruction / asthma on spirometry as compared to 22.6% children in Kottayam and Mysuru. This difference was despite the fact that two factors associated with childhood asthma, namely family history of asthma and smoker in the family, were more prevalent in Kottayam and Mysuru.
    • On spirometry, boys were observed to have a two-fold higher prevalence of asthma than girls. In Delhi, 37.2% boys had airflow obstruction/ asthma as compared to 19.9% Girls. 

    • Among the 29.3% children observed to have asthma on spirometry in Delhi, only 12% reported to have been diagnosed with asthma and only 3% used some form of inhalers. In contrast, among the 22.6% children observed to have asthma on spirometry in Kottayam and Mysuru, 27% reported to have been diagnosed and 8% were using some form of inhalers.

    • Thus, a significant number of asthmatic children are not diagnosed to have asthma and a vast majority do not receive the right treatment. This figure is much higher in Delhi as compared to Kottayam and Mysuru.


Figure 2: Gaps in the diagnosis and treatment of Asthma

 

 

Key Finding 3: Link between obesity & Asthma: High prevalence of Obesity in Delhi children and higher incidence of Asthma in them

    • 39.8% Children from Delhi were obese/overweight as compared to 16.4% children from Kottayam and Mysuru.

    • Obese/overweight children had a 79% greater chance of having asthma on spirometry across all three sites combined. This association was 38% higher in Delhi children as compared to their counterparts. 

The association between obesity/overweight in children and higher prevalence of asthma is being reported for the first time in any study from India. Ambient particulate matter air pollution has been implicated as an important cause of obesity/overweight in children in some of the most recent studies. While there could be many causes for obesity/overweight in children from Delhi, we suspect, based on the above-mentioned studies that particulate ambient air pollution could be an important contributing factor. The much higher prevalence of overweight/obesity observed in Delhi and much lower prevalence in Kottayam and Mysuru correlate very well with the reported particulate matter (PM2.5 and PM₁₀) levels in these cities.

Growing up in extremely toxic levels of air pollution can be extremely harmful for our children. In a landmark ruling in London in December 2020, a  judicial official  Philip Barlow ruled a 9 year old girl, Ella, the first person in the UK – and likely the world – to have air pollution listed as a cause of death. Ella died of severe Asthma, which was found to be because of high levels of Air Pollution. The life of millions of children in India is at risk.

Bhavreen Kandhari, a mother, said “As a mother of 2, the findings of this study horrify me. I have personally seen my children suffer in health and overall development because of high levels of Air pollution. They had to give up sports they were great at. Our children do not deserve this, they deserve clean air and a healthy environment.”

According to Air Quality Life Index, a resident of Delhi-NCR can gain 9.7 years in life expectancy if WHO Guideline is met. There is an urgent need for air pollution control measures by the government.

The alarmingly high incidence of Asthma among school students also highlights the need for national level policy on equipping schools and training teachers for handling Asthma Emergencies.

“This study has shown that around 85% of adolescent children who were found to have asthma in Delhi, did not know that they had asthma, and less than 3% of them were receiving appropriate treatment. Clearly, we need to create more awareness about asthma among parents and teachers, so that underdiagnosis and undertreatment of asthma can be significantly overcome,” said Dr Anurag Agarwal Director, CSIR – Institute of Genomics and Integrative Biology, New Delhi. The high prevalence of obesity also highlights the urgent need to control obesity by sensitizing parents and children.